Jackie’s Take: What’s On My Mind in Women’s Wellness ✍️
You’ve already asked it something personal, haven’t you?
You typed in “Should I take a new probiotic to help with my BV symptoms?” or maybe “Why do you think I’m so tired all the time?” into your fave chatbot…
And it answered. Fast, fluent, four tidy paragraphs, sounding completely sure of itself.
About one in four American adults did some version of that in the last thirty days. So let’s stop treating it as a fringe behavior and talk about it honestly.
You probably already know I use AI every single day. And I’m really excited about the future of this technology in medicine. I’ve seen AI make connections between data points for patients that left me astounded.
But we’ve got to be realistic about its limits at this point in time, especially when it comes to health.
Feed it questions about marketing or how to lay out your living room all day long.
Don’t just blindly trust it when it comes to what to do with your body.
So, as the most AI savvy person I know, let me fully explain to you exactly why you can’t blindly trust it (especially if you’re a woman!) and how to use it properly👇
The LAiDY Edit 🤖
The best prompt in health is eleven words long.
“What would you need to know about me to answer this properly?”
Ask that before you ask your actual question.
Chatbots answer as though every person asking is the same person. It won’t take your history unless you make it. That prompt makes it.
What comes back is a list. Your age, your cycle pattern, what you take, what your last labs showed, what your mother’s history is. Answer the ones you can, then ask your real question. Watch how differently it responds when it’s working from your information instead of from an average.
Try it tonight on something small.
It can still be wrong, confidently, in the same tone it uses when it’s right, so treat any answer as a first draft rather than a verdict. And whatever it gives you belongs in front of a licensed human, not instead of one.
This is the mechanic underneath The Longevity Lab. Not a chatbot guessing about you, but a copilot you’ve actually taught, running on labs and tracking you already have, with my clinical framework doing the steering. Doors open next month. Click here to get on the waitlist and snag a discount!
Worth the Click 🔗
Did you know that only around 5% of clinical trials report their results separately for women and men? Not 5% that include women. 5% that bother to say what happened to the women who were in them.
And the number I can’t shake: across a population-wide analysis spanning two decades, women were diagnosed later than men for more than 700 conditions. Four years later, on average.
I’m flagging it because it explains something you already feel, and because it’s the reason a general-purpose AI is thinner on you than on anyone else. You can’t out-Google an evidence gap.
Have you ever asked an AI chatbot a health question about yourself?
The Find 🛍️
I had a colleague recommend a book to me recently that you have to read if you haven’t yet.
It’s called All in Her Head, by Elizabeth Comen. She’s a breast cancer oncologist, now at NYU Langone’s Perlmutter Cancer Center, before that Memorial Sloan Kettering.
She goes through eleven body systems, one at a time, and lays out what medicine got wrong about women in each one, and how much of it is still sitting in the textbooks.
I’m putting it here this week because the numbers I flagged above didn’t come from nowhere. Five percent of trials reporting on women separately is the end of a very long story, and this is the book that tells it. It was a 2025 PEN/E.O. Wilson finalist, which is a science writing award, not a wellness one.
Fair warning, it will make you angry. I’d read it anyway.
Saddle Up & Spread the Word 🏇💨
If you’ve been suspicious of all of this AI stuff, forward it to the friend who asks ChatGPT about everything and then blindly trusts it. That’s how In the Saddle grows, one well woman at a time.
To share — Just click and copy this link: https://inthesaddle.beehiiv.com/
If you’re a brand, expert, or just someone with an excellent story to tell in the wellness, longevity, or sexual health space, I’d love to connect! I am always open to hearing ideas for ITS content and collabs. ✏️ 🏇🔥
With gratitude always,
Jackie Giannelli, FNP-BC, NCMP
Founder, In the Saddle
Medical Disclaimer:
The content provided in this newsletter is for informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Nothing contained herein should be construed as medical guidance or the practice of medicine. You should always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment. Never disregard professional medical advice or delay seeking care because of something you read in this newsletter. Use of the information provided is at your own risk. No clinician-patient relationship is formed through this content.

